The COVID-19 pandemic is an undisputable medical phenomenon that has reconfigured the history of our planet, almost in every facet. There’s no single sector of our planet without the aftermath implications of the pandemic.
The COVID-19 pandemic has shown how an infectious disease can sweep the globe in weeks and, in the space of a few months. By all measures, the impact of the pandemic is massive.
At the start of the COVID-19 pandemic, the BNT162b2 ( BioNtech- Pfizer) and mRNA- 1273, mRNA Vaccines were quickly developed and produced massively to curtail the spread of the virus. The production of these vaccines was a remarkable success, and the mass production was a huge success as well.
The combination of these two vaccines was effective enough to restore needed protein to patients that were tested positive, the Vaccines were not only effective for COVID-19 patients but also boosted the immune system of everyone who received the vaccine to be combat-ready to lay off any traces of the virus in people who were not yet exposed.
But just as a dagger of two sharpened sides, the distribution and clearance period of SARS coV-2 mRNA from human tissues was unclear
SARS CoV-2 mRNA Vaccine Duration In Human Tissues
To unravel the persistence and duration of this vaccine, scientists carried out a number of scientific research, RT- qPCR-based assay was developed to detect each mRNA vaccine. Lymph nodes, liver spleen, and myocardium from recently vaccinated deceased patients were screened.
Persistence traces of mRNA vaccine were present in the majority of the deceased patients those who died 30 days after vaccination, the presence was not seen in the majority of deceased patients who died more than 30 days after vaccination.
In most of the deceased patients, traces of the vaccine were not present in the liver, spleen, and mediastinal lymph nodes, but its presence was found in the myocardium of deceased patients who died within 30 days of vaccination.
The myocardium is the middle muscular layer of the heart wall.
Vaccine was also detected in the heart ventricle in deceased patients who took the vaccine within the period of 30 days, traces of injury were also detected on the ventricle wall of deceased patients with persistent mRNA with lots of myocardial macrophages as compared to the ventricle wall of deceased patients without a trace of the vaccine.
This result suggests that SAR- coV-2 mRNA vaccines persist up to 30 days from vaccination and can be found in the heart.
Cardiac Complication After SARS-CoV-2 Infection And mRNA Vaccination
SARS-CoV-2 means Severe Acute Respiratory Syndrome of COVID-19, while mRNA means the molecule in cells that carries code from DNA in the nucleus to sites of protein synthesis. In simpler terms, it means a messenger. ( It aids in the synthesis of protein from the DNA which in turn helps to boost the immune system during covid-19 complications).
Myocarditis has been recognized as a rare complication of SARS-CoV-2 mRNA vaccination, especially in young adult and adolescent males. According to the US Centers For Disease Control and Prevention, myocarditis and pericarditis rates are 12.6 cases per million doses of the second dose of mRNA vaccine among individuals 12 to 39 years of age.
In reported cases, patients with myocarditis are always presented with chest pain, usually 2-3 days after a second dose of mRNA Vaccination.
There’s little evidence to suggest a significant risk of heart failure from COVID-19 vaccination, but experts suggest that the risk of COVID-19 infection far outweighs the risk of COVID-19 vaccination.
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